Activation of Master Autophagy Regulator TFEB During Systemic LPS Administration in the Cornea

The involvement of autophagy in the cornea during the systemic inflammatory response elicited by intravenous administration of lipopolysaccharide (LPS) was investigated. Eight-week-old male Sprague-Dawley rats were injected i.v. with 15 mg/kg body weight LPS. RC4 rabbit corneal keratocytes were also...

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Autors principals: Uchida, Kyoko, Unuma, Kana, Funakoshi, Takeshi, Aki, Toshihiko, Uemura, Koichi
Format: Artigo
Idioma:Inglês
Publicat: Japanese Society of Toxicologic Pathology 2014
Matèries:
Short Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110941/
https://ncbi.nlm.nih.gov/pubmed/25352718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.2014-0004
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