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Cobalt Protoporphyrin Accelerates TFEB Activation and Lysosome Reformation during LPS-Induced Septic Insults in the Rat Heart

Lipopolysaccharide (LPS)-induced myocardial dysfunction is caused, at least in part, by mitochondrial dysfunction. Mitochondrial dysfunction and the oxidative damage associated with it are scavenged through various cellular defense systems such as autophagy to prevent harmful effects. Our recent stu...

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Detalhes bibliográficos
Main Authors: Unuma, Kana, Aki, Toshihiko, Funakoshi, Takeshi, Yoshida, Ken-ichi, Uemura, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574118/
https://ncbi.nlm.nih.gov/pubmed/23457579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056526
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