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Paraquat Induces Epithelial-Mesenchymal Transition-Like Cellular Response Resulting in Fibrogenesis and the Prevention of Apoptosis in Human Pulmonary Epithelial Cells

The aim of this study is to investigate the molecular mechanisms underlying delayed progressive pulmonary fibrosis, a characteristic of subacute paraquat (PQ) poisoning. Epithelial-mesenchymal transition (EMT) has been proposed as a cause of organ fibrosis, and transforming growth factor-β (TGF-β) i...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Yamada, Atsushi, Aki, Toshihiko, Unuma, Kana, Funakoshi, Takeshi, Uemura, Koichi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370722/
https://ncbi.nlm.nih.gov/pubmed/25799450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120192
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