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Paraquat Induces Epithelial-Mesenchymal Transition-Like Cellular Response Resulting in Fibrogenesis and the Prevention of Apoptosis in Human Pulmonary Epithelial Cells

The aim of this study is to investigate the molecular mechanisms underlying delayed progressive pulmonary fibrosis, a characteristic of subacute paraquat (PQ) poisoning. Epithelial-mesenchymal transition (EMT) has been proposed as a cause of organ fibrosis, and transforming growth factor-β (TGF-β) i...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Yamada, Atsushi, Aki, Toshihiko, Unuma, Kana, Funakoshi, Takeshi, Uemura, Koichi
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370722/
https://ncbi.nlm.nih.gov/pubmed/25799450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120192
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