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Synthesis of the novel (±)-2-methoxy-6-icosynoic acid – a fatty acid that induces death of neuroblastoma cells

The first total synthesis for the novel fatty acid (±)-2-methoxy-6-icosynoic acid was accomplished in seven steps and in a 14% overall yield starting from 2-(4-bromobutoxy)- tetrahydro-2H-pyran. The title compound displayed an EC(50) = 23 ± 1 µM against the human SHSY5Y neuroblastoma cell line and a...

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Detaylı Bibliyografya
Asıl Yazarlar: Orellano, Elsie A., Cartagena, Michelle M., Rosado, Karolyna, Carballeira, Néstor M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110677/
https://ncbi.nlm.nih.gov/pubmed/23648411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemphyslip.2013.04.004
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