Caricamento...

Synthesis of the novel (±)-2-methoxy-6-icosynoic acid – a fatty acid that induces death of neuroblastoma cells

The first total synthesis for the novel fatty acid (±)-2-methoxy-6-icosynoic acid was accomplished in seven steps and in a 14% overall yield starting from 2-(4-bromobutoxy)- tetrahydro-2H-pyran. The title compound displayed an EC(50) = 23 ± 1 µM against the human SHSY5Y neuroblastoma cell line and a...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Orellano, Elsie A., Cartagena, Michelle M., Rosado, Karolyna, Carballeira, Néstor M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110677/
https://ncbi.nlm.nih.gov/pubmed/23648411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemphyslip.2013.04.004
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !