Patient and Tumor Characteristics and BRAF and KRAS Mutations in Colon Cancer, NCCTG/Alliance N0147

BACKGROUND: KRAS and BRAF (V600E) mutations are important predictive and prognostic markers, respectively, in colon cancer, but little is known about patient and clinical factors associated with them. METHODS: Two thousand three hundred twenty-six of 3397 patients in the N0147 phase III adjuvant tri...

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Main Authors: Gonsalves, Wilson I., Mahoney, Michelle R., Sargent, Daniel J., Nelson, Garth D., Alberts, Steven R., Sinicrope, Frank A., Goldberg, Richard M., Limburg, Paul J., Thibodeau, Stephen N., Grothey, Axel, Hubbard, Joleen M., Chan, Emily, Nair, Suresh, Berenberg, Jeffrey L., McWilliams, Robert R.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110470/
https://ncbi.nlm.nih.gov/pubmed/24925349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/dju106
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