The SH2 domain interaction landscape

Members of the SH2 domain family modulate signal transduction by binding to short peptides containing phosphorylated tyrosines. Each domain displays a distinct preference for the sequence context of the phosphorylated residue. We have developed a new high-density peptide chip technology that allows...

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Main Authors: Tinti, Michele, Kiemer, Lars, Costa, Stefano, Miller, Martin, Sacco, Francesca, Olsen, Jesper V., Carducci, Martina, Paoluzi, Serena, Langone, Francesca, Workman, Christopher T., Blom, Nikolaj, Machida, Kazuya, Thompson, Christopher M., Schutkowski, Mike, Brunak, Søren, Mann, Matthias, Mayer, Bruce J., Castagnoli, Luisa, Cesareni, Gianni
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110347/
https://ncbi.nlm.nih.gov/pubmed/23545499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.03.001
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