Preconditioning Stimuli Induce Autophagy via Sphingosine Kinase 2 in Mouse Cortical Neurons

Sphingosine kinase 2 (SPK2) and autophagy are both involved in brain preconditioning, but whether preconditioning-induced SPK2 up-regulation and autophagy activation are linked mechanistically remains to be elucidated. In this study, we used in vitro and in vivo models to explore the role of SPK2-me...

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Hlavní autoři: Sheng, Rui, Zhang, Tong-Tong, Felice, Valeria D., Qin, Tao, Qin, Zheng-Hong, Smith, Charles D., Sapp, Ellen, Difiglia, Marian, Waeber, Christian
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110292/
https://ncbi.nlm.nih.gov/pubmed/24928515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.578120
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