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Sphingosine kinase 2 mediates cerebral preconditioning and protects mouse brain against ischemic injury

BACKGROUND AND PURPOSE: Cerebral preconditioning provides insights into endogenous mechanisms that protect the brain from ischemic injury. Hypoxia and the anesthetic isoflurane are powerful preconditioning agents. Recent data show that sphingosine 1-phosphate (S1P) receptor stimulation improves outc...

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Bibliographic Details
Main Authors: Yung, Lai Ming, Wei, Ying, Qin, Tao, Wang, Yumei, Smith, Charles, Waeber, Christian
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246529/
https://ncbi.nlm.nih.gov/pubmed/21980199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.111.626911
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