Regulation of Endothelial Cell Barrier Function by Antibody-driven Affinity Modulation of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1)

PECAM-1 is a 130-kDa member of the immunoglobulin (Ig) superfamily that is expressed on the surface of platelets and leukocytes, and at the intracellular junctions of confluent endothelial cell monolayers. Previous studies have shown that PECAM-1/PECAM-1 homophilic interactions play a key role in le...

Full description

Saved in:
Bibliographic Details
Main Authors: Mei, Heng, Campbell, Jay M., Paddock, Cathy M., Lertkiatmongkol, Panida, Mosesson, Michael W., Albrecht, Ralph, Newman, Peter J.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110291/
https://ncbi.nlm.nih.gov/pubmed/24936065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.557454
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items