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Regulation of Endothelial Cell Barrier Function by Antibody-driven Affinity Modulation of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1)

PECAM-1 is a 130-kDa member of the immunoglobulin (Ig) superfamily that is expressed on the surface of platelets and leukocytes, and at the intracellular junctions of confluent endothelial cell monolayers. Previous studies have shown that PECAM-1/PECAM-1 homophilic interactions play a key role in le...

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Bibliografiske detaljer
Main Authors: Mei, Heng, Campbell, Jay M., Paddock, Cathy M., Lertkiatmongkol, Panida, Mosesson, Michael W., Albrecht, Ralph, Newman, Peter J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110291/
https://ncbi.nlm.nih.gov/pubmed/24936065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.557454
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