Regulation of Endothelial Cell Barrier Function by Antibody-driven Affinity Modulation of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1)

PECAM-1 is a 130-kDa member of the immunoglobulin (Ig) superfamily that is expressed on the surface of platelets and leukocytes, and at the intracellular junctions of confluent endothelial cell monolayers. Previous studies have shown that PECAM-1/PECAM-1 homophilic interactions play a key role in le...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mei, Heng, Campbell, Jay M., Paddock, Cathy M., Lertkiatmongkol, Panida, Mosesson, Michael W., Albrecht, Ralph, Newman, Peter J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2014
Pynciau:
Cell Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110291/
https://ncbi.nlm.nih.gov/pubmed/24936065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.557454
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