Epidermal Growth Factor Receptor (EGFR) Signaling Regulates Global Metabolic Pathways in EGFR-mutated Lung Adenocarcinoma

Genetic mutations in tumor cells cause several unique metabolic phenotypes that are critical for cancer cell proliferation. Mutations in the tyrosine kinase epidermal growth factor receptor (EGFR) induce oncogenic addiction in lung adenocarcinoma (LAD). However, the linkage between oncogenic mutated...

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Main Authors: Makinoshima, Hideki, Takita, Masahiro, Matsumoto, Shingo, Yagishita, Atsushi, Owada, Satoshi, Esumi, Hiroyasu, Tsuchihara, Katsuya
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Metabolism
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110289/
https://ncbi.nlm.nih.gov/pubmed/24928511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.575464
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