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Targeting sirtuins for the treatment of diabetes

Sirtuins are a class of NAD(+)-dependent deacetylases, such as deacetylases, that have a wide array of biological functions. Recent studies have suggested that reduced sirtuin action is correlated with Type 2 diabetes. Both overnutrition and aging, which are two major risk factors for diabetes, lead...

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Main Authors: Huynh, Frank K, Hershberger, Kathleen A, Hirschey, Matthew D
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110209/
https://ncbi.nlm.nih.gov/pubmed/25067957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/dmt.13.6
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