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Differences between amyloid-β aggregation in solution and on the membrane: Insights towards elucidation of the mechanistic details of Alzheimer’s disease
The association of the amyloid-β (Aβ) peptide with cellular membranes is hypothesized to be the underlying phenomenon of neurotoxicity in Alzheimer’s disease. Misfolding of proteins and peptides, as is the case with Aβ, follows a progression from a monomeric state, through intermediates, ending at l...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4110197/ https://ncbi.nlm.nih.gov/pubmed/24464312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cs60431d |
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