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Silencing Is Noisy: Population and Cell Level Noise in Telomere-Adjacent Genes Is Dependent on Telomere Position and Sir2

Cell-to-cell gene expression noise is thought to be an important mechanism for generating phenotypic diversity. Furthermore, telomeric regions are major sites for gene amplification, which is thought to drive genetic diversity. Here we found that individual subtelomeric TLO genes exhibit increased v...

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Detalhes bibliográficos
Main Authors: Anderson, Matthew Z., Gerstein, Aleeza C., Wigen, Lauren, Baller, Joshua A., Berman, Judith
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109849/
https://ncbi.nlm.nih.gov/pubmed/25057900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004436
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