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Silencing Is Noisy: Population and Cell Level Noise in Telomere-Adjacent Genes Is Dependent on Telomere Position and Sir2

Cell-to-cell gene expression noise is thought to be an important mechanism for generating phenotypic diversity. Furthermore, telomeric regions are major sites for gene amplification, which is thought to drive genetic diversity. Here we found that individual subtelomeric TLO genes exhibit increased v...

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Autori principali: Anderson, Matthew Z., Gerstein, Aleeza C., Wigen, Lauren, Baller, Joshua A., Berman, Judith
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109849/
https://ncbi.nlm.nih.gov/pubmed/25057900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004436
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