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Inhibition of dihydroceramide desaturase activity by the sphingosine kinase inhibitor SKI II

Sphingosine kinase inhibitor (SKI) II has been reported as a dual inhibitor of sphingosine kinases (SKs) 1 and 2 and has been extensively used to prove the involvement of SKs and sphingosine-1-phosphate (S1P) in cellular processes. Dihydroceramide desaturase (Des1), the last enzyme in the de novo sy...

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Bibliografische gegevens
Hoofdauteurs: Cingolani, Francesca, Casasampere, Mireia, Sanllehí, Pol, Casas, Josefina, Bujons, Jordi, Fabrias, Gemma
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Biochemistry and Molecular Biology 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109765/
https://ncbi.nlm.nih.gov/pubmed/24875537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M049759
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