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Fusogenic selectivity of the envelope glycoprotein is a major determinant of human immunodeficiency virus type 1 tropism for CD4+ T-cell lines vs. primary macrophages.

We investigated the relationship between the fusion selectivity of the envelope glycoprotein (env) and the tropism of different human immunodeficiency virus type 1 (HIV-1) isolates for CD4+ human T-cell lines vs. primary macrophages. Recombinant vaccinia viruses were prepared encoding the envs from...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Broder, C C, Berger, E A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41096/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7568061/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.19.9004
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