Simian immunodeficiency virus variants with differential T-cell and macrophage tropism use CCR5 and an unidentified cofactor expressed in CEMx174 cells for efficient entry.

The recent identification of coreceptors that mediate efficient entry of human immunodeficiency virus type 1 (HIV-1) suggests new therapeutic and preventive strategies. We analyzed simian immunodeficiency virus (SIV) entry cofactors to investigate whether the macaque SIV model can be used as an expe...

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Pubblicato in:	J Virol
Autori principali:	Kirchhoff, F, Pöhlmann, S, Hamacher, M, Means, R E, Kraus, T, Uberla, K, Di Marzio, P
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191926/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9261370/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.9.6509-6516.1997
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