Simian immunodeficiency virus variants with differential T-cell and macrophage tropism use CCR5 and an unidentified cofactor expressed in CEMx174 cells for efficient entry.

The recent identification of coreceptors that mediate efficient entry of human immunodeficiency virus type 1 (HIV-1) suggests new therapeutic and preventive strategies. We analyzed simian immunodeficiency virus (SIV) entry cofactors to investigate whether the macaque SIV model can be used as an expe...

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Detalhes bibliográficos
Main Authors: Kirchhoff, F, Pöhlmann, S, Hamacher, M, Means, R E, Kraus, T, Uberla, K, Di Marzio, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC191926/
https://ncbi.nlm.nih.gov/pubmed/9261370
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