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Fusogenic selectivity of the envelope glycoprotein is a major determinant of human immunodeficiency virus type 1 tropism for CD4+ T-cell lines vs. primary macrophages.

We investigated the relationship between the fusion selectivity of the envelope glycoprotein (env) and the tropism of different human immunodeficiency virus type 1 (HIV-1) isolates for CD4+ human T-cell lines vs. primary macrophages. Recombinant vaccinia viruses were prepared encoding the envs from...

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Detalles Bibliográficos
Autores principales: Broder, C C, Berger, E A
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC41096/
https://ncbi.nlm.nih.gov/pubmed/7568061
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