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The deubiquitinase USP28 controls intestinal homeostasis and promotes colorectal cancer
Colorectal cancer is the third most common cancer worldwide. Although the transcription factor c-MYC is misregulated in the majority of colorectal tumors, it is difficult to target directly. The deubiquitinase USP28 stabilizes oncogenic factors, including c-MYC; however, the contribution of USP28 in...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4109555/ https://ncbi.nlm.nih.gov/pubmed/24960159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI73733 |
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