Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension

Development of the vascular disease pulmonary hypertension (PH) involves disparate molecular pathways that span multiple cell types. MicroRNAs (miRNAs) may coordinately regulate PH progression, but the integrative functions of miRNAs in this process have been challenging to define with conventional...

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Hlavní autoři: Bertero, Thomas, Lu, Yu, Annis, Sofia, Hale, Andrew, Bhat, Balkrishen, Saggar, Rajan, Saggar, Rajeev, Wallace, W. Dean, Ross, David J., Vargas, Sara O., Graham, Brian B., Kumar, Rahul, Black, Stephen M., Fratz, Sohrab, Fineman, Jeffrey R., West, James D., Haley, Kathleen J., Waxman, Aaron B., Chau, B. Nelson, Cottrill, Katherine A., Chan, Stephen Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109523/
https://ncbi.nlm.nih.gov/pubmed/24960162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74773
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