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Insights into SOD1-Linked Amyotrophic Lateral Sclerosis from NMR Studies of Ni(2+)- and Other Metal Ion-Substituted Wild Type Copper-Zinc Superoxide Dismutases()
The dimeric copper-zinc superoxide dismutase Cu(2)Zn(2)SOD1 is a particularly interesting system for biological inorganic chemical studies because substitutions of the native Cu and/or Zn ions by a non-native metal ion cause minimal structural changes and result in high enzymatic activity for those...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4109160/ https://ncbi.nlm.nih.gov/pubmed/24692094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-014-1126-5 |
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