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Allospecific Regulatory Effects of Sirolimus and Tacrolimus in the Human Mixed Lymphocyte Reaction

BACKGROUND: Tacrolimus (TAC) and sirolimus (SRL), two commonly used immunosuppressive agents, have demonstrated contrasting immunoregulatory effects. We recently described factors affecting the generation of allospecific CD4(+)CD25(High) forkhead/winged helix transcription factor P3 (FOXP3(+)) T-reg...

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Autores principales: Levitsky, Josh, Gallon, Lorenzo, Miller, Joshua, Tambur, Anat R., Leventhal, Joseph, Flaa, Catherine, Huang, Xuemei, Sarraj, Bara, Wang, Edward, Mathew, James M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109156/
https://ncbi.nlm.nih.gov/pubmed/21239962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e318200e97
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