Requirement of Cognate CD4(+) T-Cell Recognition for the Regulation of Allospecific CTL by Human CD4(+)CD127(−)CD25(+)FOXP3(+) Cells Generated in MLR

Although immunoregulation of alloreactive human CTLs has been described, the direct influence of CD4(+) Tregs on CD8(+) cytotoxicity and the interactive mechanisms have not been well clarified. Therefore, human CD4(+)CD127(−)CD25(+)FOXP3(+) Tregs were generated in MLR, immunoselected and their allos...

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Detalhes bibliográficos
Principais autores: Yu, Yuming, Miller, Joshua, Leventhal, Joseph R., Tambur, Anat R., Chandrasekaran, Dhivya, Levitsky, Josh, Luo, Xunrong, Mathew, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142165/
https://ncbi.nlm.nih.gov/pubmed/21799858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022450
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