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INHIBITORY EFFECTS OF BELATACEPT ON ALLOSPECIFIC REGULATORY T CELL GENERATION IN HUMANS
BACKGROUND: It is unclear if new co-stimulatory blockade agents, such as the CTLA-4 Ig molecule belatacept, promote or inhibit the potential for immunological tolerance in transplantation. We therefore tested the in vitro effects of BEL on human Tregs in mixed lymphocyte reactions (Treg-MLR), alone...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3800494/ https://ncbi.nlm.nih.gov/pubmed/23883971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e31829f1607 |
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