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A new approach to gene therapy using Sleeping Beauty to genetically modify clinical-grade T cells to target CD19

The advent of efficient approaches to the genetic modification of T cells has provided investigators with clinically appealing approaches to improve the potency of tumor-specific clinical grade T cells. For example, gene therapy has been successfully used to enforce expression of chimeric antigen re...

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Bibliografske podrobnosti
Main Authors: Singh, Harjeet, Huls, Helen, Cooper, Laurence JN
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109051/
https://ncbi.nlm.nih.gov/pubmed/24329797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12137
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