Imaging of Sleeping Beauty-Modified CD19-Specific T Cells Expressing HSV1-Thymidine Kinase by Positron Emission Tomography

PURPOSE: We have incorporated a positron emission tomography (PET) functionality in T cells expressing a CD19-specific chimeric antigen receptor (CAR) to non-invasively monitor the adoptively transferred cells. PROCEDURES: We engineered T cells to express CD19-specific CAR, firefly luciferase (ffLuc...

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Detalhes bibliográficos
Publicado no:Mol Imaging Biol
Main Authors: Najjar, Amer M., Manuri, Pallavi R, Olivares, Simon, Flores, Leo, Mi, Tiejuan, Huls, Helen, Shpall, Elizabeth J., Champlin, Richard E., Turkman, Nashaat, Paolillo, Vincenzo, Roszik, Jason, Rabinovich, Brian, Lee, Dean A., Alauddin, Mian, Gelovani, Juri, Cooper, Laurence J.N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096958/
https://ncbi.nlm.nih.gov/pubmed/27246312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-016-0971-8
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