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Critical role of diacylglycerol kinase-ζ in limiting B cell antigen receptor-induced ERK signaling and controlling the magnitude of the early antibody response

Signaling downstream of the B cell antigen receptor (BCR) is tightly regulated to allow for cells to gauge the strength and duration of antigen interactions and respond accordingly. In this study, we asked if metabolism of the second messenger diacylglycerol (DAG) by diacylglycerol kinase enzymes (D...

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書誌詳細
主要な著者: Wheeler, Matthew L., Dong, Matthew B., Brink, Robert, Zhong, Xiao-Ping, DeFranco, Anthony L.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108475/
https://ncbi.nlm.nih.gov/pubmed/24129701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2004189
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