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Critical role of diacylglycerol kinase-ζ in limiting B cell antigen receptor-induced ERK signaling and controlling the magnitude of the early antibody response

Signaling downstream of the B cell antigen receptor (BCR) is tightly regulated to allow for cells to gauge the strength and duration of antigen interactions and respond accordingly. In this study, we asked if metabolism of the second messenger diacylglycerol (DAG) by diacylglycerol kinase enzymes (D...

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Detalhes bibliográficos
Main Authors: Wheeler, Matthew L., Dong, Matthew B., Brink, Robert, Zhong, Xiao-Ping, DeFranco, Anthony L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108475/
https://ncbi.nlm.nih.gov/pubmed/24129701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2004189
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