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Association of diacylglycerol kinase ζ with protein kinase C α: spatial regulation of diacylglycerol signaling
Activation of PKC depends on the availability of DAG, a signaling lipid that is tightly and dynamically regulated. DAG kinase (DGK) terminates DAG signaling by converting it to phosphatidic acid. Here, we demonstrate that DGKζ inhibits PKCα activity and that DGK activity is required for this inhibit...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Rockefeller University Press
2003
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173768/ https://ncbi.nlm.nih.gov/pubmed/12629049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200208120 |
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