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Potential utility of the pan-Bcl-2 inhibitor GX15–070 (obatoclax) in cancer immunotherapy

An exploration of the immunotherapeutic potential of the pan-Bcl-2 inhibitor GX15–070 (GX15) has revealed that early-activated T cells derived from human peripheral blood are more sensitive to GX15 than are prolonged-activated T cells. Furthermore, non-memory and regulatory T cells also exhibit high...

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書目詳細資料
Main Authors: Kim, Peter S, Schlom, Jeffrey
格式: Artigo
語言:Inglês
出版: Landes Bioscience 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108468/
https://ncbi.nlm.nih.gov/pubmed/25083341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.29351
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