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Functional Role of Phosphodiesterase 3 in Cardiomyocyte Apoptosis Implication in Heart Failure
BACKGROUND: Myocyte apoptosis plays an important role in pathological cardiac remodeling and the progression of heart failure. cAMP signaling is crucial in the regulation of myocyte apoptosis and cardiac remodeling. Multiple cAMP-hydrolyzing phosphodiesterases (PDEs), such as PDE3 and PDE4, coexist...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4108189/ https://ncbi.nlm.nih.gov/pubmed/15867171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.CIR.0000165128.39715.87 |
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