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Athero-Prone Flow Activation of the SREBP2-NLRP3 Inflammasome Mediates Focal Atherosclerosis

Athero-prone flow promotes inflammation in endothelial cells, and this process is critical for pathogenesis of many chronic inflammatory conditions such as coronary and carotid artery atherosclerosis, as well as abdominal aortic aneurysm. Signal mediators activated by athero-prone (disturbed) flow t...

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Detalhes bibliográficos
Main Authors: Abe, Jun-ichi, Berk, Bradford C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091715/
https://ncbi.nlm.nih.gov/pubmed/23838164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.113.004390
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