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Pattern Recognition and Signaling Mechanisms of RIG-I and MDA5
Most organisms rely on innate immune receptors to recognize conserved molecular structures from invading microbes. Two essential innate immune receptors, RIG-I and MDA5, detect viral double-stranded RNA in the cytoplasm. The inflammatory response triggered by these RIG-I-like receptors (RLRs) is one...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4107945/ https://ncbi.nlm.nih.gov/pubmed/25101084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00342 |
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