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Murine Coronavirus Induces Type I Interferon in Oligodendrocytes through Recognition by RIG-I and MDA5

The murine coronavirus mouse hepatitis virus (MHV) induced the expression of type I interferon (alpha/beta interferon [IFN-α/β]) in mouse oligodendrocytic N20.1 cells. This induction is completely dependent on virus replication, since infection with UV light-inactivated virus could no longer induce...

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Detalhes bibliográficos
Main Authors: Li, Jianfeng, Liu, Yin, Zhang, Xuming
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903279/
https://ncbi.nlm.nih.gov/pubmed/20427526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00016-10
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