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Induction of Caspase-Dependent Apoptosis in Cultured Rat Oligodendrocytes by Murine Coronavirus Is Mediated during Cell Entry and Does Not Require Virus Replication

Murine coronavirus mouse hepatitis virus (MHV) causes demyelination of the central nervous system (CNS) in rats and mice. Apoptotic oligodendrocytes have been detected in the vicinity of the CNS demyelinating lesions in these animals. However, whether MHV can directly induce oligodendrocyte apoptosi...

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Detalhes bibliográficos
Main Authors: Liu, Yin, Cai, Yingyun, Zhang, Xuming
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC254259/
https://ncbi.nlm.nih.gov/pubmed/14581532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.22.11952-11963.2003
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