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Induction of Caspase-Dependent Apoptosis in Cultured Rat Oligodendrocytes by Murine Coronavirus Is Mediated during Cell Entry and Does Not Require Virus Replication

Murine coronavirus mouse hepatitis virus (MHV) causes demyelination of the central nervous system (CNS) in rats and mice. Apoptotic oligodendrocytes have been detected in the vicinity of the CNS demyelinating lesions in these animals. However, whether MHV can directly induce oligodendrocyte apoptosi...

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מידע ביבליוגרפי
Main Authors: Liu, Yin, Cai, Yingyun, Zhang, Xuming
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2003
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC254259/
https://ncbi.nlm.nih.gov/pubmed/14581532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.22.11952-11963.2003
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