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Induction of Caspase-Dependent Apoptosis in Cultured Rat Oligodendrocytes by Murine Coronavirus Is Mediated during Cell Entry and Does Not Require Virus Replication

Murine coronavirus mouse hepatitis virus (MHV) causes demyelination of the central nervous system (CNS) in rats and mice. Apoptotic oligodendrocytes have been detected in the vicinity of the CNS demyelinating lesions in these animals. However, whether MHV can directly induce oligodendrocyte apoptosi...

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Main Authors: Liu, Yin, Cai, Yingyun, Zhang, Xuming
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC254259/
https://ncbi.nlm.nih.gov/pubmed/14581532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.22.11952-11963.2003
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