Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate Immunity

Alpha/beta interferon immune defenses are essential for resistance to viruses and can be triggered through the actions of the cytoplasmic helicases retinoic acid-inducible gene I (RIG-I) and melanoma differentiation-associated gene 5 (MDA5). Signaling by each is initiated by the recognition of viral...

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Detalhes bibliográficos
Main Authors: Loo, Yueh-Ming, Fornek, Jamie, Crochet, Nanette, Bajwa, Gagan, Perwitasari, Olivia, Martinez-Sobrido, Luis, Akira, Shizuo, Gill, Michelle A., García-Sastre, Adolfo, Katze, Michael G., Gale, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224404/
https://ncbi.nlm.nih.gov/pubmed/17942531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01080-07
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