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The PI3K/AKT/mTOR pathway in breast cancer: targets, trials and biomarkers
The phosphoinositide 3 kinase (PI3K)/Akt/mammalian (or mechanistic) target of rapamycin (mTOR) pathway is a complicated intracellular pathway, which leads to cell growth and tumor proliferation and plays a significant role in endocrine resistance in breast cancer. Multiple compounds targeting this p...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
SAGE Publications
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4107712/ https://ncbi.nlm.nih.gov/pubmed/25057302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834014530023 |
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