Minocycline attenuates HIV-1 infection and suppresses chronic immune activation in humanized NOD/LtsZ-scidIL-2Rγ(null) mice

More than a quarter of a century of research has established chronic immune activation and dysfunctional T cells as central features of chronic HIV infection and subsequent immunodeficiency. Consequently, the search for a new immunomodulatory therapy that could reduce immune activation and improve T...

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Bibliographic Details
Main Authors: Singh, Maneesh, Singh, Pratibha, Vaira, Dolores, Amand, Mathieu, Rahmouni, Souad, Moutschen, Michel
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2014
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107666/
https://ncbi.nlm.nih.gov/pubmed/24409837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12246
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