An Improved Protocol for Efficient Engraftment in NOD/LTSZ-SCIDIL-2Rγ(NULL) Mice Allows HIV Replication and Development of Anti-HIV Immune Responses

Cord blood hematopoietic progenitor cells (CB-HPCs) transplanted immunodeficient NOD/LtsZ-scidIL2Rγ(null) (NSG) and NOD/SCID/IL2Rγ(null) (NOG) mice need efficient human cell engraftment for long-term HIV-1 replication studies. Total body irradiation (TBI) is a classical myeloablation regimen used to...

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Detalhes bibliográficos
Main Authors: Singh, Maneesh, Singh, Pratibha, Gaudray, Gilles, Musumeci, Lucia, Thielen, Caroline, Vaira, Dolores, Vandergeeten, Claire, Delacroix, Laurence, Van Gulck, Ellen, Vanham, Guido, de Leval, Laurence, Rahmouni, Souad, Moutschen, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366932/
https://ncbi.nlm.nih.gov/pubmed/22675567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038491
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