Influence of PD-L1 cross-linking on cell death in PD-L1-expressing cell lines and bovine lymphocytes

Programmed death-ligand 1 (PD-L1) blockade is accepted as a novel strategy for the reactivation of exhausted T cells that express programmed death-1 (PD-1). However, the mechanism of PD-L1-mediated inhibitory signalling after PD-L1 cross-linking by anti-PD-L1 monoclonal antibody (mAb) or PD-1–immuno...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ikebuchi, Ryoyo, Konnai, Satoru, Okagawa, Tomohiro, Yokoyama, Kazumasa, Nakajima, Chie, Suzuki, Yasuhiko, Murata, Shiro, Ohashi, Kazuhiko
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2014
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107665/
https://ncbi.nlm.nih.gov/pubmed/24405267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12243
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