Increase of cells expressing PD-L1 in bovine leukemia virus infection and enhancement of anti-viral immune responses in vitro via PD-L1 blockade

The inhibitory receptor programmed death-1 (PD-1) and its ligand, programmed death-ligand 1 (PD-L1) are involved in immune evasion mechanisms for several pathogens causing chronic infections. Blockade of the PD-1/PD-L1 pathway restores anti-virus immune responses, with concomitant reduction in viral...

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Bibliografiske detaljer
Main Authors: Ikebuchi, Ryoyo, Konnai, Satoru, Shirai, Tatsuya, Sunden, Yuji, Murata, Shiro, Onuma, Misao, Ohashi, Kazuhiko
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195098/
https://ncbi.nlm.nih.gov/pubmed/21943148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1297-9716-42-103
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