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Role of the SIK2-p35-PJA2 complex in pancreatic beta cell functional compensation
Energy sensing by the AMP-activated protein kinase (AMPK) is of fundamental importance in cell biology. In the pancreatic beta cell, AMPK is a central regulator of insulin secretion. The capacity of the beta cell to increase insulin output is a critical compensatory mechanism in prediabetes, yet its...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4107453/ https://ncbi.nlm.nih.gov/pubmed/24561619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2919 |
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