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Self-tolerance eliminates CD4(+) T, but not CD8(+) T or B, cells corrupting cancer immunotherapy
Self-tolerance, presumably through elimination of all lineages of self antigen-specific lymphocytes (CD4(+) T, CD8(+) T and B cells), creates a formidable barrier to cancer immunotherapy. In contrast to this prevailing paradigm, we demonstrate that for some antigens self-tolerance reflects selective...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4107120/ https://ncbi.nlm.nih.gov/pubmed/24771148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201444539 |
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