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Prime-Boost Immunization Eliminates Metastatic Colorectal Cancer by Producing High Avidity Effector CD8(+) T Cells
Heterologous prime-boost immunization with plasmid DNA and viral vector vaccines is an emerging approach to elicit CD8(+) T cell-mediated immunity targeting pathogens and tumor antigens that is superior to either monotherapy. Yet, mechanisms underlying the synergy of prime-boost strategies remain in...
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Publicat a: | J Immunol |
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Autors principals: | , , , , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
2017
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5435941/ https://ncbi.nlm.nih.gov/pubmed/28341670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502672 |
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