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Prime-Boost Immunization Eliminates Metastatic Colorectal Cancer by Producing High Avidity Effector CD8(+) T Cells

Heterologous prime-boost immunization with plasmid DNA and viral vector vaccines is an emerging approach to elicit CD8(+) T cell-mediated immunity targeting pathogens and tumor antigens that is superior to either monotherapy. Yet, mechanisms underlying the synergy of prime-boost strategies remain in...

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Publicat a:J Immunol
Autors principals: Xiang, Bo, Baybutt, Trevor R., Berman-Booty, Lisa, Magee, Michael S., Waldman, Scott A., Alexeev, Vitali Y., Snook, Adam E.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435941/
https://ncbi.nlm.nih.gov/pubmed/28341670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502672
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