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A de novodesigned metalloenzyme for the hydration of CO(2)[**]

Protein design will ultimately allow for the creation of artificial enzymes with novel functions and unprecedented stability. To test our current mastery of nature’s approach to catalysis, a Zn(II) metalloenzyme was prepared using de novo design. α(3)DH(3) folds into a stable single-stranded three-h...

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Detalhes bibliográficos
Main Authors: Cangelosi, Virginia M., Deb, Aniruddha, Penner-Hahn, James E., Pecoraro, Vincent L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107010/
https://ncbi.nlm.nih.gov/pubmed/24943466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201404925
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