Uncoupling between Inflammatory and Fibrotic Responses to Silica: Evidence from MyD88 Knockout Mice

The exact implication of innate immunity in granuloma formation and irreversible lung fibrosis remains to be determined. In this study, we examined the lung inflammatory and fibrotic responses to silica in MyD88-knockout (KO) mice. In comparison to wild-type (WT) mice, we found that MyD88-KO animals...

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Main Authors: Lo Re, Sandra, Yakoub, Yousof, Devosse, Raynal, Uwambayinema, Francine, Couillin, Isabelle, Ryffel, Bernard, Marbaix, Etienne, Lison, Dominique, Huaux, François
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106757/
https://ncbi.nlm.nih.gov/pubmed/25050810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099383
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