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The alarmin IL-1α is a master cytokine in acute lung inflammation induced by silica micro- and nanoparticles
BACKGROUND: Inflammasome-activated IL-1β plays a major role in lung neutrophilic inflammation induced by inhaled silica. However, the exact mechanisms that contribute to the initial production of precursor IL-1β (pro-IL-1β) are still unclear. Here, we assessed the implication of alarmins (IL-1α, IL-...
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| Veröffentlicht in: | Part Fibre Toxicol |
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| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4279463/ https://ncbi.nlm.nih.gov/pubmed/25497724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-014-0069-x |
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